Hyperin (8CI)
Hyperin
CAS: 482-36-0
Molecular Formula: C21H20O12
Hyperin (8CI) - Names and Identifiers
| Name | Hyperin |
| Synonyms | Hyperin HYPERIN HYPEROSID Hyperosid Hyperasid hyperasid Hyperozide HYPEROSIDE hyperozide Hyperoside NSC 407304 Hyperin (8CI) Quercetin-3-galactoside QUERCETIN-3-D-GALACTOSIDE Quercetin-3-O-galactoside QUERCETIN-3-O-GALACTOSIDE QUERCETIN-3B-D-GALACTOSIDE Quercetin 3-beta-D-galactopyranoside Quercetin 3-O-beta-D-galactopyranoside 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl hexopyranoside 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl D-glucopyranoside 2-(3,4-Dihydroxyphenyl)-3-(beta-D-galactopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3-(beta-D-galactopyranosyloxy)-5,7-dihydroxy- |
| CAS | 482-36-0 |
| EINECS | 207-580-6 |
| InChI | InChI=1/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15-,17+,18-,21?/m1/s1 |
Hyperin (8CI) - Physico-chemical Properties
| Molecular Formula | C21H20O12 |
| Molar Mass | 464.38 |
| Density | 1.87±0.1 g/cm3(Predicted) |
| Melting Point | 225-226°C |
| Boling Point | 872.6±65.0 °C(Predicted) |
| Specific Rotation(α) | -83°（c=0.2，pyridine） |
| Flash Point | 307.473°C |
| Solubility | Easily soluble in ethanol, methanol, acetone and pyridine. |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | Pale yellow needle crystal |
| Color | Light Yellow to Yellow |
| BRN | 5784795 |
| pKa | 6.17±0.40(Predicted) |
| Storage Condition | -20°C |
| Refractive Index | 1.803 |
| MDL | MFCD00016933 |
| Physical and Chemical Properties | Easily soluble in ethanol, methanol, acetone and pyridine. From the fruits and whole grass of the Hypericaceae family. |
Hyperin (8CI) - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R40 - Limited evidence of a carcinogenic effect |
| Safety Description | S22 - Do not breathe dust. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36 - Wear suitable protective clothing. S24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| RTECS | DJ3009200 |
| FLUKA BRAND F CODES | 10-23 |
| HS Code | 29389090 |
Hyperin (8CI) - Introduction
Hyperin is a common natural compound with the chemical name digoxin. The following is a description of the nature, use, formulation and safety information of Hyperin:
Nature:
Hyperin is a colorless crystalline solid that is sparingly soluble in water and readily soluble in ethanol, benzene and ether. It is a kind of heart glycoside compounds, has a strong cardiac effect. Hyperin undergoes metabolism in the body to form the active ingredient digoxin.
Use:
Hyperin is widely used in the treatment of heart disease, especially in the treatment of heart failure and arrhythmia. It can restore the normal function of the heart by enhancing myocardial contractility and improving atrial conduction. Hyperin is also used to treat conditions such as atrial fibrillation and ventricular fibrillation.
Preparation Method:
Hyperin is extracted from hypericum, and can be extracted by steaming or extracted from the leaves and rhizomes of Hypericum. After extraction, Hyperin was obtained by crystallization, purification and drying.
Safety Information:
Hyperin is a cardiotonic preparation with certain toxicity and side effects. It cannot be used freely and must be used under the guidance of a doctor. Improper use of Hyperin may lead to serious cardiac side effects, such as arrhythmia, tachycardia, angina, etc. At the same time, Hyperin also has renal toxicity and neurotoxicity, easy to cause nausea, vomiting and other adverse reactions. Therefore, when using Hyperin, be sure to use it strictly in accordance with the doctor's recommendations and pay close attention to the body's reaction.
Nature:
Hyperin is a colorless crystalline solid that is sparingly soluble in water and readily soluble in ethanol, benzene and ether. It is a kind of heart glycoside compounds, has a strong cardiac effect. Hyperin undergoes metabolism in the body to form the active ingredient digoxin.
Use:
Hyperin is widely used in the treatment of heart disease, especially in the treatment of heart failure and arrhythmia. It can restore the normal function of the heart by enhancing myocardial contractility and improving atrial conduction. Hyperin is also used to treat conditions such as atrial fibrillation and ventricular fibrillation.
Preparation Method:
Hyperin is extracted from hypericum, and can be extracted by steaming or extracted from the leaves and rhizomes of Hypericum. After extraction, Hyperin was obtained by crystallization, purification and drying.
Safety Information:
Hyperin is a cardiotonic preparation with certain toxicity and side effects. It cannot be used freely and must be used under the guidance of a doctor. Improper use of Hyperin may lead to serious cardiac side effects, such as arrhythmia, tachycardia, angina, etc. At the same time, Hyperin also has renal toxicity and neurotoxicity, easy to cause nausea, vomiting and other adverse reactions. Therefore, when using Hyperin, be sure to use it strictly in accordance with the doctor's recommendations and pay close attention to the body's reaction.
Last Update：2024-04-09 21:11:58
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